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Selected Publications 

Zhao, R.Y*. and M.I. Bukrinsky*. 2013. HIV-1 Viral Protein R (Vpr).  In: “Methods in Human Retrovirology”. Guido Poli (Ed). Humana.   In press. (*, co-corresponding authors)

Zhang, J. Y. Fu, G. Li, and R.Y. Zhao. 2012. Metal plasmon-coupled fluorescence imaging and label free coenzyme detection in cells.  Biochemical and Biophysical Research Communication.  425(3):696-700.

Yang, H., N.J. Nkeze, and R.Y. Zhao.  2012. Effects of HIV-1 Protease on Cellular Functions and Their Potential Applications in Antiretroviral Therapy (Review). Cell and Biosciences. Sep 12, 2(1):32.

Zhao, R.Y., G. Li, and M. Bukrinsky. 2011. Vpr-host interactions during HIV-1 viral life cycle.  Journal of Neuroimmune Pharmacology. 6(2):216-29.

Benko, Z. and R.Y. Zhao. 2011. Zeocin for selection of bleMX6 resistance in fission yeast. Biotechniques. 51(1):57-60.

Zhang, J*., Fu, Y.; Li, G., Lakowicz, J.R., R.Y. Zhao*. 2011. Fluorescent metal nanoshell and CK19 detection on single cell image. Biochemical and Biophysical Research Communication. 413(1):53-7. (*, co-corresponding authors)

Zhang, J*., Fu, Y.; Liang, D., R.Y. Zhao*, and Lakowicz, J. R. 2011. Direct observation to chemokine receptor 5 on T-lymphocyte cell surface using fluorescent metal nanoprobes 2: approximation of CCR5 populations. Biochemical and Biophysical Research Communication. 407(1):63-7. (*, co-corresponding authors)

Zhang, J*., Fu, Y.; Li,G., R.Y. Zhao*, and Lakowicz, J. R. 2011. Detection of CXCR4 receptors on cell surface using fluorescent metal nanoshell. Journal of Biomedical Optics. 16(1):016011.  (*, co-corresponding authors)

Carr, J., B. A. Osinusi, C. Flynn, B. Gilliams,  V. Maheshwari, & R.Y. Zhao. 2010. Two independent epidemics of HIV in Maryland. Journal of AIDS. 54(3):297-303.

Zhao, R.Y., D. Liang, G. Li, C.W. Larrimore, & B.L. Mirkin. 2010. Anti-cancer effect of HIV-1 viral protein R on doxorubicin resistant neuroblastoma.  PLoS One. 5(7):e11466.

Li, G., H.U. Park, D. Liang, & R.Y. Zhao. 2010.  Cell cycle G2/M arrest through an S phase-dependent mechanism by HIV-1 viral protein R.  Retrovirology. 7:59.

Li, G., R.T. Elder, L. Dubrovsky, D. Liang, T. Pushkarsky, K. Chiu, T. Fan, J. Sire, M. Bukrinsky, & R.Y. Zhao. 2010.  HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. PLoS One. 5(6):e11371.

Qin, K., L. Zhao, R.D. Ash, W.F. McDough, R.Y. Zhao. 2009. ATM-mediated transcriptional elevation of prion to copper-induced oxidative stress. Journal of Biological Chemistry. 284(7):4582-93.

Zhang, J., Fu, Y., Liang, D., Zhao, R. Y., Lakowicz, J. R. 2009. Fluorescent Adidin-bound silver particle: a novel strategy for single target molecule detection on cell membrane. Analytical Chemistry. 81(3):883-9.

Li, G., M. Bukrinsky and R.Y. Zhao. 2009. HIV-1 Viral protein R (Vpr) and its interactions with the host cell. Current HIV Research. 7(2):178-83.

Zhang, J. D. Liang, Y. Fu, R.Y. Zhao, and J.R. Lakowicz. 2008. Single Cell Fluorescence Imaging Using Metal Plasmon - Coupled Probe 2: Single Molecule Counting on Lifetime Image. Nano Letters. 8(4):1179-1186.

Zhang, J. Y. Fu, D. Liang, R.Y. Zhao and J.R. Lakowicz. 2008. Enhanced Fluorescence Images for Labeled Cells on Silver Island Films. Langmuir 24:12452-12457.

Huard, S. R.T. Elder, D. Liang, G. Li and R.Y. Zhao. 2008. HIV-1 Vpr induces cell cycle G2 arrest through Srk1/MK2-mediated phosphorylation of Cdc25. Journal of Virology 82(6):2904-2917.

Huard, S., M. Chen, K.E. Burdette, C. Fenyvuesvolgyi, M. Yu, R.T. Elder, R.Y. Zhao. 2008. HIV-1 Vpr-induced cell death is reminiscent of apoptosis in Schizosaccharomyces pombe. Cell Research. 18:961-973.

Li, L., J.Y. Li and R.Y. Zhao. 2008. APOBEC3G-UBA2 fusion as a potential strategy for stable expression of APOBEC3G and inhibition of HIV-1 replication. Retrovirology. 5:72.

Li, G., R.T. Elder, K. Qin, H.U. Park , D. Liang and R.Y. Zhao. 2007. PP2A-dependent and independent ATR phosphorylation of Chk1. 2007. Journal of Biological Chemistry. 282 (10)7287-7298.

Liang, D., Z, Benko, E. Agbottah, L. Taricani, P.G. Young, M. Bukrinsky, and R.Y. Zhao. 2007. HSP27 as a Potential Intrinsic Anti-HIV Factor Targeting HIV-1 Viral Protein R. Molecular Medicine 13(5-6):229-239.

Benko, Z., D. Liang, E. Agbottah, J. Hou, L. Taricani, P. Reed, P.G. Young, M. Bukrinsky, and R.Y. Zhao. 2007. Antagonistic interaction of HIV-1 Vpr with Hsf-mediated cellular heat shock response and Hsp16 activation in fission yeast (Schizosaccharomyces pombe). Retrovirology. 4(16):1742-1755.

Li, R. N.W. Todd, Q. Qiu, R.Y. Zhao, W.H. Rodgers, H. Fang, S.A. Stass, R.L. Katz and F. Jiang. 2007. Genetic Deletions in Sputum as Diagnostic Markers for Early Detection of Stage I Non-Small-Cell Lung Cancer. Clinical Cancer Research. 13(2):482-7.

Tao F., R. Li, N.W. Todd, Q. Qiu, H.B. Fang, H. Wang, R.Y. Zhao, N. P. Caraway, R.L. Katz, S.A. Stass, F. Jiang. 2007. Up-Regulation of 14-3-3zeta in Lung Cancer and Its Implication as Prognostic and Therapeutic Target. Cancer Research. 67(16):7901-6.

Zelivianski, S, D. Liang, M. Chen, B. L. Mirkin, R.Y. Zhao. 2006. Suppressive Effect of Elongation Factor 2 on Apoptosis Induced by HIV-1 Viral Protein R. Apoptosis. 11(3):377-88.

Zhang, Y., Qin, K., Wang, J., Hung, T.*, and R. Y. Zhao*. 2006. Dividing Roles of Prion Protein in Staurosporine-mediated Apoptosis. Biochemical and Biophysical Research Communication, 349(2):759-768. (*, co-corresponding author)

Qin, K. L. Zhao, Y. Tang, S. Bhatta, J. M. Simard, R.Y. Zhao. 2006. Doppel-induced apoptosis and counteraction by cellular prion protein in neuroblastoma and astrocytes. Neuroscience. 141(3):1375-1388.

Qin, K., M. O’Donnell, and R.Y. Zhao. 2006. Doppel: More Rival than Double to Prion. Neuroscience. 141(1):1-8.

Fenyvesvolgyi, C. R.T. Elder, Z. Benko, D. Liang, and R.Y. Zhao. 2005. Fission yeast homologue of Tip41-like proteins regulates type 2A phosphatases and responses to nitrogen sources. Biochimica et Biophysica Acta. 1746(2):155-62.

Daniel, R. E. Marusich, E. Argyris, R.Y. Zhao, A.M. Skalka and R.J. Pomerantz. 2005. Caffeine inhibits human immunodeficiency virus type 1 transduction of nondividing cells. Journal of Virology. 79(4):2058-65.

Zhao, R.Y., and R.T. Elder. 2005. Viral Infections and cell cycle G2/M regulation (invited review). Cell Research. 15(3):143-9.

Zhao, R.Y. 2005. From single cell gene-based diagnostics to diagnostic genomics: current applications and future perspectives. Clinical Laboratory Sciences. 18(4):254-262.

Constantine, N.T. and R.Y. Zhao. 2005. Molecular-based laboratory testing and monitoring for human immunodeficiency virus infections. Clinical Laboratory Sciences. 18(4):263-270.

Constantine, N.T., William Kabat and R.Y. Zhao. 2005. Update on diagnosis and monitoring of human immunodeficiency virus infections in China. In: “HIV/AIDS in China” R.Y. Zhao (ed.). Cell Research. 15(11-12):870-876.

Li, L., Li, H., C.D. Pauza, M. Bukrinsky and R.Y. Zhao. 2005. HIV-host interaction: role of accessory proteins. In: “HIV/AIDS in China” R.Y. Zhao (ed.). Cell Research. 15(11-12):923-934.

Zhao, R.Y. and R.T. Elder. 2005. Viral infections and cell cycle G2/M control. Cell Research.15(3):143-9. (featured article on the cover of the journal)

Benko, Z., D. Liang, E. Agbottah, J. Hou, K. Chiu, M. Yu, S. Innis, P. Reed, W. Kabat, R.T. Elder, P. Di Marzio, Ratner, P.G. Young, M. Bukrinsky and R.Y. Zhao. 2004. Anti-Vpr activity of a yeast chaperone protein. Journal of Virology. 78(20):11016-11029.

Iordanskiy, S., Y. Zhao, L. Dubrovsky, T. Iordanskaya, M. Chen, D. Liang, and M. Bukrinsky. 2004. Heat-shock protein 70 protects cells from HIV-1 infection by targeting viral protein R. Journal of Virology. 78(20):9697-9704.

Iordanskiy, S.*, Y. Zhao*, P. DiMarzio, I. Agostini, L. Dubrovsky, and M. Bukrinsky. 2004. Heat-shock protein 70 exerts opposite effects on Vpr-dependent and Vpr-independent HIV-1 replication in macrophages. Blood  104(6):1867-1872. (* equal contribution).

Bukrinsky, M. and Y. Zhao. 2004. Heat-shock proteins reverse the G2 arrest caused by HIV-1 viral protein R. DNA and Cell Biology. 23(4):223-5.

Elder R.T., X. Zhu, S. Priet, M. Chen, M. Yu, J.M. Navarro, J. Sire, and Y. Zhao. 2003. A fission yeast homologue of the human uracil-DNA glycosylase and their roles in causing DNA damage from overexpression. Biochemical and Biophysical Research Communication 306:693-700.

Zhao, Y. 2003. Association overstated? (Letter to the editor). June 12. Re: Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis. Journal of Clinical Investigation. 111:1547-1554.

Zhao, Y., M. Chen, J. Yang, R.T. Elder, X.Q. Song, B. Wang, M. Yu, and N. Saksena. 2002. Functional conservation of HIV-1 Viral protein R (Vpr) and its potential association with disease progression of HIV-infected patients. Virus Research 89(1):103-121

Elder, R.T., Song, X-q, M. Chen, K.M. Hopkins, H.B. Lieberman and Y. Zhao. 2002. Involvement of Rhp23, a S. pombe orthologue of the Human HHR23A and S. cerevisiae Rad23 nucleotide excision repair genes, in cell cycle control and protein ubiquitination. Nucleic Acid Research, 30(2):581-591.

Elder, R.T., M. Yu, M. Chen, X. Zhu, M. Yanagida and Y. Zhao. 2001. HIV-1 Vpr induces G2 arrest in fission yeast (Schizosaccharomyces pombe) through a pathway involving regulatory and catalytic subunits of PP2A and acting on both Wee1 and Cdc25. Virology 287:359-370.

Elder, R.T., M.Yu, M. Chen, S. Edelson and Y. Zhao. 2000. Cell cycle G2 arrest induced by HIV-1 Vpr in fission yeast (Schizosaccharomyces pombe) is independent of cell death and early genes in the DNA damage checkpoint. Virus Research, 68(2):161-173.

Chen, M., Elder, R. T., Yu, M., O'Gorman, M., Selig, L., Benarous, R., Yamamoto, A., and Zhao, Y. 1999. Mutational analysis of Vpr-induced G2 arrest, nuclear localization and cell death in fission yeast. Journal of Virology 73:3236-3245.

Zhao, Y., M.Yu, M.Z. Chen, R.T. Elder, A. Yamamoto and J. Cao. 1998. Pleiotropic effects of HIV-1 protein R (Vpr) on morphogenesis and cell survival in fission yeast and antagonism by pentoxifylline. Virology 246:266-276.

Zhao, Y., J. Cao, M. R.G. O'Gorman, Min Yu and R. Yogev. 1996. Effect of human immunodeficiency virus Type 1 protein R (vpr) gene expression on basic cellular functions of fission yeast Schizosaccharomyces pombe. Journal of Virology70(9):5821-5826.

Zhao, Y. and H.B. Lieberman. 1995. Schizosaccharomyces pombe: a model system for molecular studies of eukaryotic genes. DNA and Cell Biology 14(5):359-371.

Zhao, Y., L. Goriparthi, and H.B. Lieberman. 1994. A new shuttle vector system for the identification of spontaneous and radiation-induced mutations in the fission yeast Schizosaccharomyces pombe. Mutation Research 311:111-123.


Li, YM, and Y. Zhao (eds) Practical Protocols in Molecular Biology. Science Press, New York Ltd. 1995 (First printing), 1996 (Second printing), 1997 (First translation into Chinese), 2000 (Second printing of the Chinese version).

View more Publications by from the Zhaolab listed in the National Library of Medicine (PubMed).


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